Stress is a condition that has an immense negative effect on human health, including our mental health, but also the health of our skin. This is known as the brain-skin axis. This axis works both ways: lack of sleep, for instance, can cause visible impact of stress on the skin: skin breaks out, becomes blotchy, dry and sensitive – a vicious circle of negative influence resulting in a loss of well-being. Neuromediators produced in the skin, signal to the brain, causing neurogenic inflammation, i.e., itch and pain. AnnonaSense CLR™ is able to break this cycle through its agonistic effect on the CB2-receptor which regulates the brain-skin-interaction and is thus able to re-establish a homeostatic balance.
If you want to learn more about the efficacy and consumer perception of AnnonaSense CLR™ and how it can convince the critical “clean” beauty consumer, read our article in Pharmaceutical & Cosmetic Review by Harald van der Hoeven (Director Product Design & Development) and Nathalia Gruber (Director Marketing & Corporate Communications).