Our skin’s microbiome is set to become an integral part of skincare regimens in the future. A growing number of cosmetic brands anticipate on this by launching new products either positively influencing the ‘health’ of the skin microbiome or making use of ingredients based on microbes, mostly probiotics, or both. The question is, what is a healthy skin microbiome? And how can we make improvements in the skin microbiome? Is there room for improvement at all? What cosmetically relevant outcomes can be expected?